Jan H J Hoeijmakers Selected Research

A-Form DNA (A-DNA)

2/2007	Retinal degeneration and ionizing radiation hypersensitivity in a mouse model for Cockayne syndrome.
5/2002	Premature aging in mice deficient in DNA repair and transcription.

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Jan H J Hoeijmakers Research Topics

Disease

15	Neoplasms (Cancer) 03/2021 - 07/2004
9	DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes) 04/2024 - 07/2004
6	Trichothiodystrophy Syndromes 01/2021 - 05/2002
6	Xeroderma Pigmentosum (Kaposi's Disease) 02/2016 - 01/2002
5	Inflammation (Inflammations) 04/2024 - 02/2010
5	Reperfusion Injury 11/2020 - 02/2010
5	Cockayne Syndrome (Syndrome, Cockayne) 02/2007 - 01/2002
4	Hypersensitivity (Allergy) 01/2019 - 12/2005
3	Sarcopenia 04/2024 - 08/2022
3	Genomic Instability 02/2016 - 08/2008
3	Breast Neoplasms (Breast Cancer) 02/2016 - 05/2014
2	Premature Aging 12/2023 - 12/2006
2	Skin Neoplasms (Skin Cancer) 02/2016 - 01/2005
2	Ischemia 06/2011 - 05/2011
2	Insulin Resistance 02/2010 - 04/2009
2	Hypoglycemia (Reactive Hypoglycemia) 01/2007 - 12/2006
1	Body Weight (Weight, Body) 04/2024
1	Left Ventricular Dysfunction 03/2024
1	Heart Failure 03/2024
1	Nervous System Diseases (Neurological Disorders) 01/2023
1	Hyperthyroidism 01/2023
1	Hypogonadism (Hypergonadotropic Hypogonadism) 01/2023
1	Frailty 01/2023
1	Obesity 01/2023
1	Folic Acid Deficiency (Folic Acid Deficiencies) 01/2023
1	Complementation Group G Xeroderma Pigmentosum 01/2023
1	Vitamin B 12 Deficiency (Vitamin B12 Deficiency) 01/2023
1	Neurodevelopmental Disorders 01/2021
1	Osteoporosis 01/2019
1	Polyploidy 01/2019
1	Fever (Fevers) 12/2017
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2017
1	Chromosome Breakage 02/2016
1	Complementation Group C Xeroderma Pigmentosum 01/2015
1	Urinary Bladder Neoplasms (Bladder Cancer) 01/2015
1	Wounds and Injuries (Trauma) 12/2014
1	Inborn Genetic Diseases (Disease, Hereditary) 12/2014

Drug/Important Bio-Agent (IBA)

13	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2002
6	DNA (Deoxyribonucleic Acid)IBA 02/2016 - 12/2005
4	NucleotidesIBA 04/2009 - 08/2006
3	Biomarkers (Surrogate Marker)IBA 04/2024 - 01/2015
3	Growth Hormone (Somatotropin)IBA 01/2023 - 12/2006
3	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 04/2009
3	Transcription Factor TFIIHIBA 01/2019 - 07/2004
2	Indicators and Reagents (Reagents)IBA 04/2024 - 03/2024
2	Liver GlycogenIBA 04/2024 - 01/2007
2	EndonucleasesIBA 01/2023 - 02/2016
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2023 - 02/2016
2	nicotinamide-beta-ribosideIBA 01/2022 - 01/2022
2	MicroRNAs (MicroRNA)IBA 05/2014 - 12/2011
2	AntioxidantsIBA 02/2010 - 01/2007
2	A-Form DNA (A-DNA)IBA 02/2007 - 05/2002
2	Insulin-Like PeptidesIBA 01/2007 - 12/2006
2	Deoxyribodipyrimidine Photo-LyaseIBA 11/2006 - 01/2005
1	succinyl-coenzyme A (succinyl-CoA)IBA 04/2024
1	Alanine (L-Alanine)FDA Link 04/2024
1	malic acid (malate)IBA 04/2024
1	Glutathione Disulfide (GSSG)FDA LinkGeneric 04/2024
1	11-hydroxy-5,8,12,14-eicosatetraenoic acidIBA 04/2024
1	Dinoprostone (PGE2)FDA Link 04/2024
1	Prostaglandin D2IBA 04/2024
1	prostaglandin F1IBA 04/2024
1	8,9-epoxyeicosatrienoic acidIBA 04/2024
1	9-hydroxy-10,12-octadecadienoic acidIBA 04/2024
1	GlycogenIBA 04/2024
1	iodothyronine deiodinase type IIBA 12/2023
1	Thyroid HormonesIBA 12/2023
1	Carboplatin (JM8)FDA LinkGeneric 01/2023
1	Cisplatin (Platino)FDA LinkGeneric 01/2023
1	Amino Acids FDA Link 08/2022
1	LipidsIBA 08/2022
1	AminesIBA 08/2022
1	Acarbose FDA LinkGeneric 01/2022
1	sodium nitrateIBA 01/2022
1	idebenoneIBA 01/2022
1	ResveratrolIBA 01/2022
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2022
1	Ibuprofen (Motrin)FDA LinkGeneric 01/2022
1	Metformin (Glucophage)FDA LinkGeneric 01/2022
1	NAD (NADH)IBA 01/2022
1	TrehaloseIBA 01/2022
1	Sirolimus (Rapamycin)FDA Link 01/2021
1	SulfurIBA 01/2021
1	LigandsIBA 01/2019
1	Activins (Activin)IBA 01/2019
1	PlatinumIBA 10/2018
1	transcription factor TFIIE (TFIIE)IBA 12/2017
1	Tryptophan (L-Tryptophan)FDA Link 01/2017
1	CytokinesIBA 01/2017
1	Doxorubicin (Adriamycin)FDA LinkGeneric 02/2016
1	NexusIBA 01/2016
1	platelet-derived growth factor AIBA 12/2014
1	Platelet-Derived Growth FactorIBA 12/2014
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 09/2014
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 09/2014
1	ProteomeIBA 07/2014

Therapy/Procedure

9	Diet Therapy (Therapy, Diet) 04/2024 - 02/2010
5	Therapeutics 04/2024 - 05/2014
3	Drug Therapy (Chemotherapy) 02/2016 - 07/2004
1	Cranial Irradiation 01/2023